Exosomal miRNA in chemoresistance, immune evasion, metastasis and progression of cancer

Kulkarni B.; Kirave P.; Gondaliya P.; Jash K.; Jain A.; Tekade R.K.; Kalia K.

Full metadata record

DC Field	Value	Language
dc.contributor.author	Kulkarni B.	en_US
dc.contributor.author	Kirave P.	en_US
dc.contributor.author	Gondaliya P.	en_US
dc.contributor.author	Jash K.	en_US
dc.contributor.author	Jain A.	en_US
dc.contributor.author	Tekade R.K.	en_US
dc.contributor.author	Kalia K.	en_US
dc.date.accessioned	2023-11-30T08:58:05Z	-
dc.date.available	2023-11-30T08:58:05Z	-
dc.date.issued	2019	-
dc.identifier.issn	1359-6446	-
dc.identifier.other	EID(2-s2.0-85069750973)	-
dc.identifier.uri	https://dx.doi.org/10.1016/j.drudis.2019.06.010	-
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/986	-
dc.description.abstract	In the treatment of cancer, there are three significant limitations causing high mortality and recurrence rates among cancer patients. First, the escape of tumor cells from the immune system	en_US
dc.description.abstract	second, the development of multi‐drug resistance (MDR) to chemotherapeutic drugs	en_US
dc.description.abstract	and, third, the noxious metastases of cancer cells. Exosomes are vesicular cargos involved in the transportation of miRNA, mRNA and proteins from one cell to another cell. This review details the current understanding of the exosomal transmission of miRNA and crosstalk with the downstream consequences, ultimately leading to the progression and metastasis of cancer. Further, this review also discusses how exosomal miRNA can provide promising novel targets for the treatment and detection of cancer. © 2019 Elsevier Ltd	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier Ltd	en_US
dc.source	Drug Discovery Today	en_US
dc.title	Exosomal miRNA in chemoresistance, immune evasion, metastasis and progression of cancer	en_US
dc.type	Review	en_US
Appears in Collections:	Review