Methods and approaches for determination and enantioseparation of (RS)-propranolol

Batra S.; Bhushan R.

Full metadata record

DC Field	Value	Language
dc.rights.license	All Open Access, Bronze	-
dc.contributor.author	Batra S.	en_US
dc.contributor.author	Bhushan R.	en_US
dc.date.accessioned	2023-11-30T08:57:28Z	-
dc.date.available	2023-11-30T08:57:28Z	-
dc.date.issued	2019	-
dc.identifier.issn	0269-3879	-
dc.identifier.other	EID(2-s2.0-85054183218)	-
dc.identifier.uri	https://dx.doi.org/10.1002/bmc.4370	-
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/956	-
dc.description.abstract	Propranolol, a β-adrenergic receptor antagonist, is a chiral compound that is marketed as a racemate, but only the (S)-(−)-enantiomer is responsible for the β-adrenoceptor blocking activity. Different chromatographic methods have been applied for separation and determination of enantiomers of (RS)-propranolol. In this article a review is presented on different liquid chromatographic methods used for enantioseparation of (RS)-propranolol, using both HPLC and TLC. In addition, some aspects of enantioseparation under achiral phases of liquid chromatography have been briefly mentioned. © 2018 John Wiley & Sons, Ltd.	en_US
dc.language.iso	en	en_US
dc.publisher	John Wiley and Sons Ltd	en_US
dc.source	Biomedical Chromatography	en_US
dc.subject	(RS)-propranolol	en_US
dc.subject	chiral derivatization agents	en_US
dc.subject	chiral stationary phase	en_US
dc.subject	Enantioseparation	en_US
dc.subject	HPLC	en_US
dc.subject	ligand exchange	en_US
dc.subject	TLC	en_US
dc.title	Methods and approaches for determination and enantioseparation of (RS)-propranolol	en_US
dc.type	Review	en_US
Appears in Collections:	Review