http://10.10.120.238:8080/xmlui/handle/123456789/870
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tamanna | en_US |
dc.contributor.author | Hussain Y. | en_US |
dc.contributor.author | Sharma D. | en_US |
dc.contributor.author | Chauhan P. | en_US |
dc.date.accessioned | 2023-11-30T08:52:15Z | - |
dc.date.available | 2023-11-30T08:52:15Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0022-3263 | - |
dc.identifier.other | EID(2-s2.0-85128674185) | - |
dc.identifier.uri | https://dx.doi.org/10.1021/acs.joc.2c00215 | - |
dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/870 | - |
dc.description.abstract | A highly enantio- and diastereoselective synthesis of highly functionalized isochromans was achieved through an organocatalyzed domino reaction. Quinidine as the catalyst initiates a peroxyhemiacetalization/oxa-Michael/desymmetrization domino sequence between various 2,5-cyclohexadienone-tethered aryl aldehydes with hydroperoxides to generate the single diastereomers of isochromans appended with a cyclohexenone ring bearing three vicinal stereocenters in good yields and high enantioselectivities under ambient reaction conditions. © 2022 American Chemical Society. | en_US |
dc.language.iso | en | en_US |
dc.publisher | American Chemical Society | en_US |
dc.source | Journal of Organic Chemistry | en_US |
dc.title | Asymmetric Synthesis of Cyclohexenone-Fused Isochromans via Quinidine-Catalyzed Domino Peroxyhemiacetalization/Oxa-Michael Addition/Desymmetrization Sequence | en_US |
dc.type | Journal Article | en_US |
Appears in Collections: | Journal Article |
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