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Please use this identifier to cite or link to this item: http://10.10.120.238:8080/xmlui/handle/123456789/870
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dc.contributor.authorTamannaen_US
dc.contributor.authorHussain Y.en_US
dc.contributor.authorSharma D.en_US
dc.contributor.authorChauhan P.en_US
dc.date.accessioned2023-11-30T08:52:15Z-
dc.date.available2023-11-30T08:52:15Z-
dc.date.issued2022-
dc.identifier.issn0022-3263-
dc.identifier.otherEID(2-s2.0-85128674185)-
dc.identifier.urihttps://dx.doi.org/10.1021/acs.joc.2c00215-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/870-
dc.description.abstractA highly enantio- and diastereoselective synthesis of highly functionalized isochromans was achieved through an organocatalyzed domino reaction. Quinidine as the catalyst initiates a peroxyhemiacetalization/oxa-Michael/desymmetrization domino sequence between various 2,5-cyclohexadienone-tethered aryl aldehydes with hydroperoxides to generate the single diastereomers of isochromans appended with a cyclohexenone ring bearing three vicinal stereocenters in good yields and high enantioselectivities under ambient reaction conditions. © 2022 American Chemical Society.en_US
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.sourceJournal of Organic Chemistryen_US
dc.titleAsymmetric Synthesis of Cyclohexenone-Fused Isochromans via Quinidine-Catalyzed Domino Peroxyhemiacetalization/Oxa-Michael Addition/Desymmetrization Sequenceen_US
dc.typeJournal Articleen_US
Appears in Collections:Journal Article

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