http://10.10.120.238:8080/xmlui/handle/123456789/538| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jafari E. | en_US |
| dc.contributor.author | Chauhan P. | en_US |
| dc.contributor.author | Kumar M. | en_US |
| dc.contributor.author | Chen X.-Y. | en_US |
| dc.contributor.author | Li S. | en_US |
| dc.contributor.author | von Essen C. | en_US |
| dc.contributor.author | Rissanen K. | en_US |
| dc.contributor.author | Enders D. | en_US |
| dc.date.accessioned | 2023-11-30T08:40:59Z | - |
| dc.date.available | 2023-11-30T08:40:59Z | - |
| dc.date.issued | 2018 | - |
| dc.identifier.issn | 1434193X | - |
| dc.identifier.other | EID(2-s2.0-85044782107) | - |
| dc.identifier.uri | https://dx.doi.org/10.1002/ejoc.201800034 | - |
| dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/538 | - |
| dc.description.abstract | A new protocol for the organocatalytic asymmetric synthesis of highly functionalized tetrahydrocarbazoles has been developed based on a vinylogous Michael/aldol reaction sequence between 3-(trifluoroacetyl)-2-methyl-indoles and enals. This formal [4+2] annulation occurs by cooperative catalysis between an achiral Brønsted base and a chiral secondary amine organocatalyst to afford tetrahydrocarbazole products bearing three vicinal stereocenters, including a trifluoromethylated tetrasubstituted stereocenter, in excellent yields, diastereo- and enantioselectivities. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Wiley-VCH Verlag | en_US |
| dc.source | European Journal of Organic Chemistry | en_US |
| dc.subject | Annulation | en_US |
| dc.subject | Asymmetric synthesis | en_US |
| dc.subject | Organocatalysis | en_US |
| dc.subject | Tetrahydrocarbazoles | en_US |
| dc.subject | Trifluoromethylation | en_US |
| dc.title | Organocatalytic Asymmetric Synthesis of Trifluoromethylated Tetrahydrocarbazoles by a Vinylogous Michael/Aldol Formal [4+2] Annulation | en_US |
| dc.type | Journal Article | en_US |
| Appears in Collections: | Journal Article | |
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